Effective management of liver fluke in cattle can be based on a ‘4 Point Plan’:
Where there is confirmed resistance to triclabendazole, careful use of all the remaining actives will be necessary. Just switching to closantel or nitroxynil (the next on the list for ability to kill immature fluke) will lead to overuse of this active and will then generate resistance to closantel or nitroxynil too. So far there have been no confirmed cases of resistance to either actives in the UK. However in other parts of the world there is already significant levels of closantel resistance in sheep. If closantel is overused here in the UK, it is not a case of if resistance occurs, but when.
Combinex™ Oral Suspension for cattle contains 7.5% w/v levamisole hydrochloride and 12% w/v triclabendazole. Fasinex™ 240 Oral Suspension for cattle contains 24% w/v triclabendazole. Legal category: POM-VPS. Information regarding the side effects, precautions, warnings and contra-indications can be found in product packaging and leaflets; further information can also be found in the Summary of Product Characteristics. Advice should be sought from the prescriber prior to use. Use Medicines Responsibly (www.noah.co.uk/responsible). Elanco™, Combinex™, Fasinex™ and the diagonal bar are trademarks of Elanco or its affiliates. PM-UK-20-0673
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